ベトナム共産党の正統性と国会の選挙・運営を通した民主的正統性の主張

早大学位記番号:新8375早稲田大

Impacts of κ- oligocarrageenan application on photosynthesis, nutrient uptake and bean yield of coffee (Coffea robusta)

κ-Oligocarrgeenan (OC) is well known as an effective and green plant growth promoter and elicitor. However, its effect on coffee plant has not been investigated so far. This study aimed to examine the impacts of OC on biophysical activity, vegetative growth and productivity of coffee plant (Coffea robusta). OC with average molecular weight (AMW) of 4.0 kDa was prepared by depolymerization of carrageenan using ascorbic acid. Field experiments were conducted by foliar spray four times per year at various OC concentrations (50, 100, 150, 200, and 250 ppm) for three years (2017-2019). The results showed that OC promoted growth of coffee plant in all tested concentrations, and an optimized concentration was found at 150 ppm which showed a significant increase compared to the control plant in total chlorophyll (24.79%), carotenoid (31.65%), uptakes of N (15.66%), P (15.81%), and K (22.25%) minerals in leaves, crop yield (19.80%) and bean size (13.10%). Therefore, OC is potentially promising to apply as a promoter to enhance yield of crops for sustainable coffee plantation

Applied bioinformatics tools for analysis of Microrna-214 expression and prediction of its potential targets genes in Nasopharyngeal carcinoma

miRNA (microRNA) are short RNA molecules in length from 20 to 24 nucleotides that have been shown to play an important role in regulating gene expression in many different types of human cancer. Meanwhile, miRNA-214 is one of the known miRNAs involved in the formation of nasopharyngeal carcinoma (NPC) through overexpression that promotes proliferation and development of cancer cells. However, in Vietnam, the study of miR-214 related to NPC has not been conducted yet. With the aims to develop the further studies of miR-214 on NPC in Vietnamese patients, in this initial study, we conducted the analysis of miR-214 expression in previous publications, as well as the prediction of miR-214 potential target genes, which involved in many cellular pathways. Here we applied bioinformatics tools to predict miRNAs and their targets, and discuss the role of miR-214 in the context of human cancers. As the results, miR-214 acted as the oncogenic roles in NPC, relevanted to many pathways, such as cell proliferation, apoptosis, metastasis and invasion through the its target genes LTF, Bim, Bax, LINC0086, etc. In conclusion, the use of computional approaches facilitate the further experimental validation of miRNAs in general, particularly miR-214, in Vietnamese NPC patients

Numerical simulation of all-normal dispersion visible to near-infrared supercontinuum generation in photonic crystal fibers with core filled chloroform

This study proposes a photonic crystal fiber made of fused silica glass, with the core infiltrated with chloroform as a new source of supercontinuum (SC) spectrum. We numerically study the guiding properties of the fiber structure in terms of characteristic dispersion and mode area of the fundamental mode. Based on the results, we optimized the structural geometries of the CHCl3-core photonic crystal fiber to support the broadband SC generations. The fiber structure with a lattice constant of 1 μm, a filling factor of 0.8, and the diameter of the first-ring air holes equaling 0.5 μm operates in all-normal dispersion. The SC with a broadened spectral bandwidth of 0.64 to 1.80 μm is formed by using a pump pulse with a wavelength of 850 nm, 120 fs duration, and power of 0.833 kW. That fiber would be a good candidate for all-fiber SC sources as cost-effective alternative to glass core fibers